Which adverse effect should a client using acetazolamide (Diamox) daily report to their physician?

A client taking acetazolamide (Diamox) daily should report dark urine to their physician as this can indicate a potentially serious adverse effect. Acetazolamide is a carbonic anhydrase inhibitor often used to treat conditions like glaucoma, altitude sickness, and certain types of seizures. One of the less common but significant side effects is the potential for renal impairment, which can lead to hematuria (blood in urine) or changes in urine coloration.

While nausea, urinary frequency, and decreased appetite can be common side effects of acetazolamide, dark urine is more concerning. It could suggest issues like hematuria or other conditions related to the kidneys or liver that require immediate medical attention. Monitoring for changes in urine color is essential, as it can be an indicator of underlying problems that need to be addressed. Therefore, any instance of dark urine should be taken seriously and reported to a healthcare provider as it may necessitate further investigation.